Biointerfaces
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Surfaces are crucial in biology, and in LSST, we are engaged in research of relevance to implants, to understanding the way in which nature lubricates, and its imitation, as well as with novel approaches to the reduction of biofouling. Many of our approaches involve techniques and approaches that we have developed in other areas of research, including gradients and polymer brushes.
References
- external page Imparting Nonfouling Properties to Chemically Distinct Surfaces with a Single Adsorbing Polymer: A Multimodal Binding Approach
Ângela Serrano, Stefan Zürcher, Samuele Tosatti and Nicholas D. Spencer
Macromolecular Rapid Communications; 2016; 37(7) pp 622-629 - external page Orthogonal Morphological Feature-Size and Density Gradients for Exploring Synergistic Effects in Biology
Clément V.M. Cremmel, Christian Zink, Katharina Maniura-Weber, Lucio Isa, and Nicholas D. Spencer
Langmuir; 2015; 31(30) pp 8446-8452 - external page The role of nanostructures and hydrophilicity in osseointegration: In-vitro protein-adsorption and blood-interaction studies
Brigitte S. Kopf, Sylvie Ruch, Simon Berner, Nicholas D. Spencer, Katharina Maniura-Weber
Journal of Biomedical Materials Research: Part A; 2015; 103(8) pp 2661-2672 - external page Differential regulation of osteogenic differentiation of stem cells on surface roughness gradients
Faia-Torres A.B., Guimond-Lischer S., Rottmar M., Charnley M., Goren T., Maniura-Weber K., Spencer N.D., Textor M., Reis R.L., Neves N.M.
Biomaterials; 2014; 35(33) pp 9023-9032 - external page Nonfouling response of hydrophilic uncharged polymers
Ângela Serrano, Olof Sterner, Sophie Mieszkin, Stefan Zürcher, Samuele Tosatti, Maureen E. Callow, James A. Callow and Nicholas D. Spencer
Advanced Functional Materials; 2013; 23(46) pp 5706 - 5718 - external page Orthogonal nanometer-micrometer roughness gradients probe morphological influences on cell behavior
Christian Zink, Heike Hall, Don M. Brunette and Nicholas D. Spencer
Biomaterials; 2012; 33(32) pp 8055-8061